Lorlatinib, a third-generation anaplastic lymphoma kinase (ALK)/receptor tyrosine kinase inhibitor (ROS1), demonstrated efficacy in ROS1 positive (ROS1+) non-small cell lung cancer (NSCLC), although approval is currently limited to the treatment of ALK+ patients.However, lorlatinib-induced resistance mechanisms, and its efficacy against the resista

Abstract This research analyzes the impact of identity politics and Pancasila based peace religiosity on the behavior of religious people in the Special Region of Yogyakarta.Identity politics is used in relation to its negative understanding, while Pancasila-based peace religiosity is understood positively, to contract the Power Inlet Module two.Us

Aptamers are nucleic acid ligands which exhibit specific binding to a desired target.Oligonucleotides are limited in their ability to form hydrophobic interactions.The affinity of aptamers can be improved with the introduction of hydrophobic modifiers into the structure of nitrogenous bases.Click-SELEX is a powerful tool used for the development of

This article aims to provide an in-depth research into the importance of English silver, the oldest of the traditional crafts that served the social, aesthetic and Board Game functional needs of English nobility and aristocracy for centuries, in the British market, economy, design and culture, in general, in the late eighteenth and early nineteenth

The Eastern Route of the South-to-North Water Diversion Project is a national strategic measure to improve the water supply conditions of the cities along the route, Jiaodong and Huaibei regions.However, the Water Diversion Project not only brings social and economic benefits, but also changes the hydrological situation and Snow Cone Maker ecologic